| abstract |
The present invention relates to compounds of hydantoins and methods of using such compounds for the treatment of age-related diseases such as androgen receptor related conditions such as prostate cancer, and pharmaceutical compositions containing such compounds. In one embodiment, the pharmaceutical composition comprises a therapeutically effective amount of a compound according to Formula II, or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier, diluent or adjuvant. The present invention provides a series of compounds that modulate the function of nuclear hormone receptors, particularly androgen receptors. These compounds can cause the disappearance of prostate cancer cells and tumors. |