| abstract |
The present invention relates to novel heteroaryl substituted benzothiazole derivatives, precursors thereof, and therapeutic uses of such compounds having the following structural formula (I), as well as their pharmaceutically acceptable salts, compositions and Regarding usage. The invention further relates to novel heteroaryl-substituted benzothiazole derivatives suitable for imaging amyloid deposits in patient organisms, their compositions, methods of use and methods of making such compounds. More specifically, the present invention relates to a method of imaging brain amyloid deposits in vivo, which enables biodiagnosis of Alzheimer's disease and measurement of clinical effects of therapeutic agents for Alzheimer's disease. [Chemical 1] |