| abstract |
The present invention provides imidazole derivatives of formula (I-IV), processes for their preparation, pharmaceutical compositions comprising compounds of formula (I-IV), and their use in the treatment of human or animal disorders. The compounds of the present invention inhibit protein tyrosine phosphatase 1B and may thus be useful for the management, treatment, control or adjunct treatment of diseases mediated by PTPase activity. Such diseases include type I diabetes and type II diabetes. |