abstract |
Disclosed are methods and drugs for modulating the interaction of CBP or p300 with β-catenin or γ-catenin. Drugs that increase CBP binding to β-catenin are associated with enhancing β-catenin-related proliferation of adult stem cells including hematopoietic stem cells, neural stem cells, skin stem cells, and islet stem cells as well as embryonic stem cells Yes. |