| abstract |
A novel method for producing an MRI-like contrast agent for imaging with high sensitivity and high resolution is provided. [MEANS FOR SOLVING PROBLEMS] Step 1 of dehydration condensation reaction of two molecules of sugar lactone and one molecule of diethylenetriamine, Step 2 of addition reaction of two molecules of the step and one molecule of DTPA-dianhydride, and one molecule of the result of step 2 And a step 3 of forming a complex reaction with one molecule of gadolinium chloride, and a method for producing a gadolinium complex represented by the following general formula (1). (In the formula, G 1 represents a residue obtained by reacting a sugar lactone with an amino group.) [Selection figure] None |