| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_983fa366d54b080542742d72951c002c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ca3b5e06b416c3a11ec7bb26ee8a3537 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-40 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-531
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-564
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-573
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-577 |
| filingDate |
2007-12-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aa6117d137cc03aa24f25205914fe32d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4a0fa15fd72406066f2c60bb691eb94a |
| publicationDate |
2009-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2009156615-A |
| titleOfInvention |
Method for measuring PAD4 and anti-PAD4 antibody and method for detecting rheumatoid arthritis |
| abstract |
[Problem] To provide means capable of accurately detecting PAD4 in blood and means capable of detecting anti-PAD4 autoantibodies with high accuracy, which are useful for detecting rheumatoid arthritis with high accuracy. The method of measuring PAD4 in a test sample of the present invention is to immunize a test sample brought into contact with a calcium ion chelating agent using a monoclonal antibody that reacts with PAD4 in an antigen-antibody reaction or an antigen-binding fragment thereof. Measuring PAD4 that may be contained in the test sample. The method for measuring an anti-PAD4 autoantibody in a test sample of the present invention comprises binding a monoclonal antibody that reacts with PAD4 to an antigen antibody or an antigen-binding fragment thereof to a solid phase, and the monoclonal antibody or antigen thereof on the solid phase. Immunize anti-PAD4 autoantibodies produced against PAD4 in vivo by sandwich method using antigen-immobilized solid phase prepared by binding PAD4 antigen to binding fragment Including measuring. [Selection] Figure 3 |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104360062-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3266872-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11447569-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11613580-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012026309-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021231879-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-7217631-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2019523759-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-4223786-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2014516155-A |
| priorityDate |
2007-12-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |