| abstract |
The present invention provides an anti-HIV drug having antiviral action, particularly HIV integrase inhibitory activity. A compound (I) of the following formula and an anti-HIV drug containing the same. Wherein Z 1 is NR 4 ; R 1 is hydrogen or lower alkyl; X is a single bond, a heteroatom group selected from O, S, SO, SO 2 and NH, or the heteroatom group is Optionally substituted lower alkylene or lower alkenylene; R 2 is optionally substituted aryl; R 3 is hydrogen, halogen, hydroxy, optionally substituted lower alkyl, etc .; R 4 and Z 2 are together To form a ring to form a polycyclic compound (including tricyclic or tetracyclic compounds). [Selection figure] None |