| abstract |
Dendritic polymers with enhanced expandability and internal functionality are described. These dendritic polymers combine rapid ring-opening chemistry (or other fast reactions) with the use of branched cell reagents in a controlled manner, often resulting in a single product with a clean chemical structure. Easy to expand on a commercial scale because it is manufactured by building a dendritic structure constructed quickly and precisely using generations, and requires less reagent and less dilution Thus, a new range of materials can be manufactured, and a low cost and high production capacity method is provided. The dendritic polymer composition produced has novel internal functionalities, high stability (eg, high thermal stability, little or no reverse Michael reaction), and a surface density that causes encapsulation at lower generations To reach. Unexpectedly, the reaction of these multifunctional branched cell reagents with the multifunctional core does not yield a cross-linked material. Such dendritic polymers are oil / water emulsions, wet strength agents in the paper industry, proton scavengers, polymers, nanoscale monomers, electron microscope calibration standards, production of size selective membranes, And as a viscosity modifier in aqueous compositions such as paint. When these dendritic polymers have a supported material associated with their surfaces and / or interiors, these dendritic polymers may further perform, for example, drug delivery, transfection, and diagnostics due to their unique properties. It has the property of transporting materials as it does. The method of the present invention provides a precise structure with a clean chemistry process, typically a single product, requires less reagent excess and less dilution. It provides a method that is easy to scale to commercial scale, can produce a new range of materials, is low cost and has high production capacity. |