| abstract |
A new type of contrast agent that includes substrate particles with a plurality of metal nanoparticles has been described as well as a method for imaging therewith. The plurality of metal nanoparticles are encapsulated in non-proteinaceous biocompatible or biodegradable matrix particles and / or non-proteinaceous biocompatible or biodegradable Attached to the substrate particles, wherein the substrate particles are selected from the group consisting of carbohydrates, lipids, synthetic polymers, aqueous liquids, surfactants, and organic liquids, or mixtures thereof. Is done. The matrix particles are biocompatible and / or biodegradable and can be bound to a targeted molecule for targeted visualization. |