abstract |
The present invention, R 1, R 2, R 3, R 4, R 5, R 6, R 7, X and Z are as defined herein, the formula (I), (II), (III) or In regard to compounds having (IV), pharmaceutical compositions containing the compounds as well as for the treatment of disorders associated with human 11-β-hydroxysteroid dehydrogenase type 1 enzyme and for human 11-β-hydroxysteroid dehydrogenase 1 It relates to a method of using the present compounds for the preparation of drugs acting on type enzymes. |