abstract |
To elucidate the pharmacological action of Withanone contained in Ashwagandha leaf extract, and to provide a composition for new pharmaceutical use and health use based on the pharmacological action. SOLUTION: With a life span of normal cells, induction and maintenance of proteasome activity of normal cells, protective action against oxidative stress of normal cells, ultraviolet rays of normal cells, containing Withanone or a derivative thereof as an active ingredient Protection against DNA damage or chemical toxicity, activity of glucose-6-phosphodehydrogenase (G6PD) in normal cells or treatment of G6PD deficiency, therapeutic action or prevention of tumor or cancer, or anticancer agent for cancer cells A composition for enhancing sensitivity. [Selection figure] None |