| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0669f10ac82c082c17a3bf9d4a941b96
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5ef4e459dae0beb9149db1eec84d20ee |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-04 |
| filingDate |
2007-02-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a80dd12ec45df31a4d1d44342f002307
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8b868ec02b26cdbda2fca4db17bc9022
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f3b5187b9b412663887e8670e28bdb21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5360ba84c9550d8d5f66dd01fa3d43df |
| publicationDate |
2008-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2008193912-A |
| titleOfInvention |
Screening method for therapeutic agents for heart failure |
| abstract |
PROBLEM TO BE SOLVED: To provide a method for evaluating and identifying a therapeutic agent for heart failure using a heart failure model zebrafish. A method for selecting a candidate substance for a therapeutic agent for heart failure, comprising administering a test substance to zebrafish that exhibits heart failure symptoms induced by tacrolimus hydrate, measuring the expression of the PECI gene, and testing Disclosed is a method comprising the steps of selecting a test substance as a candidate drug for treating heart failure when expression of the PECI gene is suppressed as compared to when not administering the substance when administered. The The method of the present invention is useful for screening for a therapeutic agent for heart failure using a heart failure model zebrafish. [Selection] Figure 4 |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102520130-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111973594-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-WO2019130745-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-7103605-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019130745-A1 |
| priorityDate |
2007-02-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |