abstract |
【Task】 In addition to suppressing the bitterness and unpleasant odor of the drug at the time of taking, provide an orally administered preparation with good release of the drug from the preparation in the digestive tract such as the gastrointestinal tract. [Solution] The drug particles are coated with a gastric polymer, and the coated particles have a structure in which an acidic substance that promotes dissolution of the polymer is disposed inside the coating layer. This coated particle is further granulated into granules or granules, or formed into tablets with excipients, and is an oral dosage form that is easy to take and easy to release drugs. |