http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2008007489-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fec576c38e34882531ca37d6b922bf42 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-07 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C209-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B53-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C211-29 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C209-62 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B53-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C211-29 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C209-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C209-84 |
| filingDate | 2006-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d19ca73dd4430ea506bff6d957e2f482 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f54c83196360dd9a103e7d0b7c4d2666 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6e53fe3f245427232b2821ab44ca675f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dd9c94cb75c25d75b0c5734b72b5af4c |
| publicationDate | 2008-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2008007489-A |
| titleOfInvention | Process for producing optically active 1- (fluoro, trifluoromethyl or trifluoromethoxy substituted phenyl) alkylamine N-monoalkyl derivatives |
| abstract | The present invention provides an industrial process for producing optically active 1- (fluoro, trifluoromethyl or trifluoromethoxy substituted phenyl) alkylamine N-monoalkyl derivatives which are important intermediates for pharmaceuticals and agricultural chemicals. A fluoro, trifluoromethyl or trifluoromethoxy substituted phenyl alkyl ketone and an optically active primary amine are converted to an optically active imine by dehydration condensation, and then the imine is present in a hydrogen gas atmosphere in the presence of a transition metal catalyst. To an optically active secondary amine by asymmetric reduction, and further, reductive alkylation of the secondary amine and formaldehyde (including equivalents) or lower aldehyde in the presence of a transition metal catalyst in a hydrogen gas atmosphere By converting to an optically active tertiary amine and finally subjecting the tertiary amine to hydrogenolysis, the target optically active compound can be produced efficiently. [Selection figure] None |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012025822-A1 |
| priorityDate | 2006-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 309.