| abstract |
The present invention relates to detecting a target by moving the target close to a surface that has an affinity for the target. This migration involves the use of electrophoresis, which can be enhanced by the presence of oxidizing and reducing agents that reduce the voltage at which the electrophoretic force can be generated. This lower potential allows the detection of the target, eg, means of detection during concentration and the ability to detect multiple times without immobilizing the target. Tags can be coupled to the target to provide movement and / or detectability. The target is a molecule, such as a nucleic acid or protein, and is conveniently a microorganism. Microorganisms may be immobilized and grow when immobilized on a surface, allowing identification of the susceptibility of the microorganism to various antimicrobial agents. |