| abstract |
Compounds of formula I that are useful herein as protein kinase inhibitors Or a pharmaceutically acceptable salt thereof is described. Here, ring B, Z 1 , Z 2 , U, p, Q, R 1 , R 2 , R 3 , and R 3 are defined herein. These compounds and their pharmaceutically acceptable compositions are useful for treating various disorders or reducing the severity of those disorders. These disorders include stroke, inflammatory disorders, autoimmune diseases such as systemic lupus erythematosus or psoriasis, proliferative disorders such as cancer, and conditions related to organ transplantation. |