| abstract |
Oral aerosol sprays or capsules using polar or non-polar solvents with ondansetron that are rapidly absorbed by the oral mucosa and have immediate effects have been developed. The intraoral polar composition of the present invention has a formulation 1: aqueous polar solvent, ondansetron and optional flavor, formulation 2: aqueous polar solvent, ondansetron, optional flavor and propellant, formulation 3: nonpolar Solvent, Ondansetron and optional flavor, Formula 4: Nonpolar solvent, Ondansetron, optional flavor and propellant, Formula 5: Mixture of polar and dipolar solvents, Ondansetron and optional flavor , Formulation 6: with polar and non-polar solvent mixture, ondansetron, optional flavoring and propellant. |