abstract |
【Task】 It is possible to provide a crystal composed of a complex of a glucocorticoid receptor ligand binding domain and a ligand having a non-steroid skeleton. [Solution] Glucocorticoids are de receptor ligand binding domain and hexagonal crystal system containing a conjugate with a ligand, space group belong to P6 1, unit cell a = 126.0 ± 4.0 Å, b = 126. 0 plus or minus 4.0 angstrom, c = 72.6 plus or minus 4.0 angstrom, α = β = 90 °, γ = 120 °, and the ligand is a ligand having a non-steroidal skeleton Crystal etc. [Selection figure] None |