| Predicate |
Object |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09B69-103
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09B69-109
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09B11-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09B15-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P19-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09B57-02 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N-
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate |
2004-02-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
2006-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2006524040-A |
| titleOfInvention |
Terminal phosphate-labeled nucleotides with novel linkers |
| abstract |
Methods for enhancing substrate properties of terminal phosphate-labeled nucleotides for enzymes, nucleic acid detection methods, and manganese complexes of terminal phosphate-labeled nucleotides. PROBLEM TO BE SOLVED: To describe methods for enhancing their substrate properties for various enzymes using terminal phosphate-labeled nucleotides in the presence of a manganese salt. In particular, methods for detecting nucleic acids in a sample based on the use of terminal phosphate labeled nucleotides as substrates for nucleic acid polymerases in the presence of a manganese salt are described. Further provided are terminal phosphate-labeled nucleotides and manganese complexes of terminal phosphate-labeled nucleotides with enhanced substrate properties and novel linkers. The presence of a manganese salt increases the enzyme substrate property of terminal phosphate-labeled nucleotides, and the method of detecting nucleic acids in a sample using the same and the terminal phosphate-labeled nucleotides having novel linkers therefor are used. Manganese complexes are provided. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11155851-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2018537969-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11396677-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2011514809-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-7023842-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8791246-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2017515887-A |
| priorityDate |
2003-02-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |