| abstract |
The present invention relates to immunogenic compositions and vaccines for the treatment and prevention of Neisseria disease. The immunogenic composition of the present invention comprises a combination of antigens selected from at least two different classes of antigens including adhesins, autotransporter proteins, toxins, iron acquisition proteins and membrane bound proteins (preferably integral outer membrane proteins). Containing. Such antigen combinations can be targeted to immune responses against various aspects of the life cycle of Neisseria and can cause more effective immune responses. |