| abstract |
【Task】 In the surface modification of a substrate in which a radiation labile compound is introduced to the substrate surface by irradiation, a surface modification method capable of greatly reducing the modification of the compound by radiation, and the surface modification method The resulting modified substrate is provided. [Solution] A modified substrate obtained by irradiating a substrate in contact with a compound unstable to radiation in the presence of an organic solvent, and the substrate is a hollow fiber membrane or the like A separation membrane is used, and as the compound, a compound having an amino acid as a constituent element, particularly a compound having blood anticoagulant activity is preferably used. [Selection figure] None |