| abstract |
The present invention provides a method for producing a cell-immobilized substrate capable of forming a new cell adhesion patterning and changing its size after cell seeding, particularly under cell culture. A compound in which a terminal functional group is protected by a photodegradable protecting group is immobilized on a substrate, and at least a part of the photodegradable protecting group is removed by light irradiation to thereby remove at least a part of the terminal functional group. And adsorbing cells to at least a part of the exposed terminal functional group, or adsorbing a cell adhesion-inhibiting substance to at least a part of the photodegradable protecting group, and irradiating with light, the cell adhesion-inhibiting substance At least a part of the photodegradable protecting group adsorbed to expose at least a part of the terminal functional group and adsorb cells to at least a part of the exposed terminal functional group, or the exposed A method for adsorbing a cell adhesion promoting substance on at least a part of a terminal functional group and adsorbing cells on at least a part of the cell adhesion promoting substance, and a substrate. [Selection figure] None |