| Predicate |
Object |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0056
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0032
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0058 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-44
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B10-00 |
| filingDate |
2003-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
2005-08-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2005523945-A |
| titleOfInvention |
In vivo imaging of apoptosis |
| abstract |
The present invention relates to conjugates and methods for in vivo imaging of apoptosis using a conjugate of a fluorescent dye and a moiety that specifically binds to apoptotic cells. In certain embodiments, the fluorescent dye is conjugated to a moiety that emits near-infrared fluorescence and specifically binds to apoptotic cells, such as annexin A5 or synaptotagmin. The method is non-invasive and can be used to obtain images of apoptotic cells in tissues of living animals such as mammals such as humans. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9649355-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1953661-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8809497-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-6109067-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2007154066-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9849197-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2011506590-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012118136-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2020518240-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2009511566-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9682122-B2 |
| priorityDate |
2002-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |