| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9df90d7822cc480ce12c480f4089e229
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_77702c1ce54414fc07700422641a6883
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_769252eb4db2cc00320830be2c5cdb56 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-127 |
| filingDate |
2004-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_33413d1f3a158b6c039e91a16a14ae83
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_86b936f5b5a03dfbf724720f3e4cc2ea
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_43a749a421b94058e7b8708f0ed2f6ca
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2e67ba3d40509bceadaff4df9aa146ee
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b0c41a516883d18f27c1d838ee908993 |
| publicationDate |
2005-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2005298407-A |
| titleOfInvention |
Polycation-modified liposome and production method thereof |
| abstract |
PROBLEM TO BE SOLVED: To provide a cationic liposome that can be used as a gene carrier without a problem of cytotoxicity. SOLUTION: A polycation-modified liposome obtained by modifying the surface of a liposome whose main component is phospholipid with chitosan and a solution of a liposome whose main component is phospholipid are dropped into an acidic solution of chitosan. And a substance to be encapsulated in the liposome in a mixed fluid containing phospholipid, chitosan and carbon dioxide under a temperature and / or pressure higher than the critical point of carbon dioxide. The manufacturing method of the polycation modification liposome characterized by adding the aqueous phase containing this. [Selection] Figure 1 |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2013136038-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018101349-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115105447-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2013100332-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006080157-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2656858-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112006288-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9750694-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2133097-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8449979-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115105447-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2133097-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8658204-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2016175363-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10098841-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012090498-A1 |
| priorityDate |
2004-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |