| abstract |
SUMMARY A PEG-chitosan conjugate comprising a chitosan and a polyethylene glycol moiety or derivative thereof that is conjugated and integrated, and its use in medicine, is described. In one embodiment, the conjugate comprises a chitosan moiety or derivative thereof and a polyethylene glycol moiety or derivative thereof linked together via an amino functionality on chitosan by use of an activated chitosan species. In another embodiment, the conjugate comprises a chitosan moiety or derivative thereof and a polyethylene glycol moiety bound together with the chitosan moiety of the conjugate of a molecular weight in the range of 10 kilodaltons to 1000 kilodaltons. |