| abstract |
【Task】 Provided is a cyclosporine preparation that can be easily and inexpensively manufactured, has excellent stability, has improved self-emulsification rate when contacted with water, and has reduced solubility and variation in medicinal effects. [Solution] Substantially free of oil components, (a) at least one cyclosporine, (b) a reaction product of natural or hydrogenated castor oil and ethylene oxide, and (c) a pharmaceutically acceptable carbon number of 1 to (A) 6 to 40%, (b) 20 to 70%, and (c) 10 to 60% by weight of the four alcohols (a) to (c), where the total amount of the three components is 100. Composition. [Selection figure] None |