| abstract |
The present invention relates to a compound represented by the general formula (I) wherein R 2a and R 2b independently represent hydrogen, halogen, lower alkoxy, cyano, -COOH, lower alkoxycarbonyl, or lower alkyl (which is R 3a , R 3b independently of one another are hydrogen, lower alkyl, lower cycloalkyl, or, when taken together, — (CH 2 ) n — (n Is 2, 3 or 5)]. The compound represented by the formula (I) is, for example, 2- (3,5-bis-trifluoromethyl-phenyl) -N-methyl-N- (6-morpholin-4-yl-4-o-tolyl-pyridine -3-yl) -isobutylamide and 2- (3,5-bis-trifluoromethyl-phenyl) -N-methyl-N- (2-morpholin-4-yl-4-o-tolyloxy-pyrimidine-5- It is a useful intermediate for preparing therapeutically active compounds such as yl) -isobutylamide. |