http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2004517089-A
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-00 |
filingDate | 2001-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2004-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2004517089-A |
titleOfInvention | Method for preparing phosphorothioate oligonucleotides |
abstract | Assembling the oligonucleotide bond to the solid support in the presence of acetonitrile, and prior to cleaving the oligonucleotide from the solid support, removing acetonitrile, and cleaving the oligonucleotide from the solid support, A process for the synthesis of a phosphorothioate oligonucleotide is provided. The process is particularly suitable for large-scale synthesis of nucleotides. Acetonitrile may be removed from the solid support by one or both of drying and solvent washing. Preferred washing solvents include trialkylamines. |
priorityDate | 2000-12-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 96.