| abstract |
Disclosed is a clinical application of the beta 3 agonists, the most desirable blood levels for its efficacy even in the presence of various factors that increase blood insulin concentration that may affect the expression, beta 3 agonists efficacy expression The provision of a formulation that can control the The present invention provides a blood concentration control formulation consisting beta 3 adrenergic receptor agonists, long to sustain blood levels, to sustain increased blood levels after a certain time has passed, the blood after a predetermined time has elapsed Oral solid preparations, transdermal preparations, solution preparations, suppositories, inhalants, or raw materials that have the function of increasing and rapidly decreasing the concentration and of increasing and decreasing the blood concentration periodically and at controlled intervals. Degradable implant preparation. [Selection diagram] None |