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filingDate 2003-02-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d7f3c39283487b3aed7f4c28aae3dd3c
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publicationDate 2004-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2004238348-A
titleOfInvention Itraconazole formulation for oral administration
abstract [Object] To develop an itraconazole preparation having high bioavailability and to develop an efficient and inexpensive production method of such preparation. A biological material in which itraconazole is adsorbed and / or coated on a core substance made of silicic acid or a salt thereof by a spray drying method or a melting method with a solution of itraconazole dissolved in methylene chloride or the like. Itraconazole granules for oral administration with improved bioavailability and granules, tablets and capsules were prepared from such granules. [Selection diagram] Fig. 1
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