| abstract |
(57) [Summary]nThe present invention provides a method of treating a neoplasm using a combination therapy comprising a target cell-specific and replicable adenovirus vector and chemotherapy, radiation therapy or a combination thereof. The specific type of neoplasm in need of treatment, and in combination with chemotherapy and / or radiation, synergistic treatment compared to existing adenovirus or conventional chemotherapy and radiation For certain types of neoplasms as achieved, adenoviral vectors are target cell-specific. |