abstract |
PROBLEM TO BE SOLVED: To provide a method for producing a biaryl compound by a coupling reaction between a halogen-substituted aryl compound and an arylboronic acid, a derivative thereof or a dialkyl-arylborane, which can be easily produced in a higher yield than before. To provide an industrially advantageous method. SOLUTION: In producing a biaryl compound by reacting a halogen-substituted aryl compound with an arylboronic acid, a derivative thereof or a dialkyl-arylborane in a solvent in the presence of a base and a solvent-insoluble palladium catalyst, a dialkyl-aryl is used. The reaction is performed in the presence of phosphine. |