| abstract |
(57) [Summary] [Problem] A matrix metalloprotease (MMP) Provided are compounds having excellent activity inhibitory activity against s), and MMPs inhibitors, pharmaceutical compositions, cosmetic compositions, and external preparations containing the same as active ingredients. SOLUTION: The dithiazole compound of the formula (I) or a salt thereof. Embedded image [R 1 is a hydrogen atom, alkyl, etc .; R 2 is a hydrogen atom, hydroxy, alkyl, aryl, arylalkoxy, arylalkyl, etc .; R 3 is any group of formulas (II) to (IV): Embedded image Embedded image |