| abstract |
(57) [Problem] To provide a culture substrate, a cell array, an automatic injection device of a chemical substance, and an assay system necessary for easily assaying various chemical substances such as drugs and poisons. SOLUTION: A region coated with a cell-adhesive polymer is arranged minutely and irregularly discontinuously, and a region coated with a non-cell-adhesive hydrophilic polymer is surrounded therearound. A substrate for a high-density cell array is used in which a region coated with an adherent, strongly hydrophobic material has a surface continuously surrounding. This high-density cell array substrate and an assay system using the same optimize the type of drug (eg, anticancer drug) and the concentration used, thereby greatly reducing the side effects of the drug and the disease. It is possible to greatly improve drug treatment results. In addition, this technology can be used for drug development, environmental assessment, and basic life science research, and is an extremely effective technology. |