abstract |
(57) Abstract: A novel method for medical treatment and / or suppression of progression of osteoporosis, breast cancer, hypercholesterolemia, high fat crystals or atherosclerosis in warm-blooded animals including humans, Selective estrogen receptor modulators, in particular of the general formula (I) And a compound selected from the group consisting of dehydroepiandrosterone, dehydroepiandrosterone sulfate, androst-5-ene-3β, 17β-diol, and compounds that are converted in vivo to these compounds. A method comprising the administration of an amount of a steroid precursor. Also disclosed is the administration of the biciphosphonates with a selective estrogen receptor modulator and / or sex steroid precursor for the medical treatment and / or prevention of progression of osteoporosis. Pharmaceutical compositions and kits useful in the present invention are also provided. |