| Predicate |
Object |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-35
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-43527 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-095 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-35
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-435 |
| filingDate |
1997-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
2001-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2001521907-A |
| titleOfInvention |
Tolerogenic fragments of natural allergens |
| abstract |
(57) [Summary]nPROBLEM TO BE SOLVED: To provide a tolerogenic fragment of a natural allergen.nThe present invention relates to a method for the controlled enzymatic cleavage of purified and decolorized active allergenic proteins from indoor and outdoor source materials, which method retains a natural T-lymphocyte stimulating epitope. , Resulting in fragments of the allergen depleted of IgE-binding B-cell epitopes and complement-activators. The invention also relates to a new pharmaceutical product. These allergen fragments do not present the disadvantages of conventional allergenic extracts for immunotherapy and are used safely to induce specific T cell anergy and immunological tolerance states in allergic humans be able to. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2010504278-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2015051979-A |
| priorityDate |
1997-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |