| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4756
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4705
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-71 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B82B1-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-475
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-71
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00 |
| filingDate |
1997-07-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
2000-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2000515372-A |
| titleOfInvention |
Chimeric heteromultimeric adhesive |
| abstract |
SUMMARY A chimeric heteromultimeric adhesive that binds a ligand for a natural heteromultimeric receptor, and uses thereof, are disclosed. The heteromultimeric adherent chimeric molecule contains an extracellular domain of the heteromultimeric receptor monomer and a multimerization domain for stable interaction of the chimeric molecule at the adherent. In particular, heteromultimeric adhesives comprising the extracellular domains of ErbB2 and ErbB3 or ErbB2 and ErbB4 are disclosed. The chimeric ErbB heteromultimeric adhesive of the present invention is useful as a competitive antagonist or agonist of neuregulin for the treatment of various diseases such as cancer. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-4660094-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2009525762-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2005533488-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2010213710-A |
| priorityDate |
1996-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |