| abstract |
[57] [Problem] To provide a long-term medical material that exhibits excellent antithrombotic properties and biocompatibility suitable for medical materials such as various catheters, guidewires, artificial blood vessels, hemodialysis membranes, and endoscopes. The manufacturing method is provided. A surface of a substrate (A) is provided with the following general formula (1): (Wherein, R 1 , R 2 and R 3 may be the same or different groups and represent a hydrogen atom or a monovalent hydrocarbon group having 1 to 4 carbon atoms. And a copolymer (B) based on a monomer having a group capable of bonding to heparin or a heparin derivative, and a heparin or heparin derivative (having an integer of 4). A medical material comprising a coating layer formed of C). |