| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_41686a979f961bce6a9855b4b409a5b8 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-91 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-15
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-483
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-84
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02 |
| filingDate |
1998-11-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e189c290c77492b50da5ffc239bd13a3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9410d107bb445865df4e85d1f907da03 |
| publicationDate |
2000-05-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2000139462-A |
| titleOfInvention |
Rapid screening system for drug absorption by measuring intracellular pH change |
| abstract |
(57) [Problem] To provide an evaluation method capable of rapidly evaluating intestinal absorption of a drug in vitro. SOLUTION: (1) a step of forming a cell layer; and (2) (4) a step of introducing a fluorescent dye into the cell layer; (3) a step of bringing the cell layer into which the fluorescent dye is introduced into contact with a buffer solution containing a drug to absorb the drug into the cell layer; Evaluating the abundance of the drug in the cells by fluorescence analysis of the pH change in the cells of the cell layer obtained in (3), and evaluating the intestinal absorption of the drug. . |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2365336-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2365337-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015045516-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2015066129-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2011231127-A |
| priorityDate |
1998-11-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |