abstract |
The present invention relates to a process for the preparation of novel alkenic acid derivatives of the formula I, wherein X is a nitrile group or a (C 14) alkoxycarbonyl group, and Y is -COOZ or -CONRR ', wherein Z is C 1-4 alkyl. , R and R 'are phenyl or benzyl. or R and R ', together with the nitrogen atom, represent a morphine ring. by reducing a new compound of formula II wherein X and Y are as defined above. The novel compounds produced are intermediates of thienamycin and related compounds. y-ch2 y-CH2 X • ch3 |