http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-969772-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_571b8abacacea64d3f7089d0983b8b3b |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-02 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-02 |
| filingDate | 1961-01-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b3779b5a33ca1010cc66e794cc8a73e5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8870f0191cedabf5a49c9986670f6f3a |
| publicationDate | 1964-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-969772-A |
| titleOfInvention | Toxoids and their production |
| abstract | Toxoids are obtained from purified bacterial toxins by treating said toxins in an aqueous medium with formaldehyde in the presence of an aliphatic diamine of molecular weight below 200 which contains a primary or secondary amino group. The toxoids are believed to be represented by the formula [t] (CH2.Y)n, in which [t] represents the radical formed from a bacterial toxin molecule by the loss of one or more hydrogen atoms on groups reactive with formaldehyde, Y represents the radical formed by the loss of a hydrogen atom from an amino group of a molecule of an aliphatic diamine of molecular weight below 200, and n is a positive number. Specified aliphatic diamines, as defined above, are lysine and ethylenediamine. The said aliphatic diamines may be used in admixture with other amines, e.g. alanine. Examples illustrate the preparation of diphtheria toxoids, aqueous solutions of which may be used as diphtheria vaccines, including diphtheria-tetanus and diphtheria-pertussiotetanus vaccines. According to the Provisional Specification, arginine is a further example of a suitable aliphatic diamine, as defined above. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2592137-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2495341-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9040058-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-690518-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6060067-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9403206-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2495341-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2498112-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-102011118371-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-102011122891-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013068568-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2014500269-A |
| priorityDate | 1961-01-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 33.