http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2372256-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b1f5f76c9a55e2c323d6ae4bbf23af7d |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09B57-007 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-582 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-58 |
| filingDate | 2001-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8265bcd1ffb7df8062e6ec1dc0528cb5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6826f5c85f462e49b20d019f69321b70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e26a5b686f04e6b1647f4c21e5a95179 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_87e4de47422cfe544a7632cf7bee5bce |
| publicationDate | 2002-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-2372256-A |
| titleOfInvention | Detectable entity comprising a plurality of detectable units releasably connected together by stimulus-cleavable linkers for use in fluorescence detection |
| abstract | In a technique for signal amplification in fluorescence detection or other analytical-detection techniques such as colourimetric or visual detection, a detectable unit (eg a fluorescent dye) is joined together with similar detectable units by means of a linker. The linker is designed to be cleaved in response to a preselected stimulus to release the individual detectable units. The linker may be selected from the group consisting of: phosphodiester linkages (eg as in figure 5); other enzyme-cleavable linkages; amide linkages; other photocleavable linkages; co-ordination complexes between a metal ion and a ligand; other acid-cleavable linkages; other base-cleavable linkages; ester linkages; ether linkages; silicon-based group linkages; acetal-based linkages; aminal-based linkages; orthoester-based linkages; orthoamide based linkages; and combinations of two or more of the above. The preselected stimulus may be selected from the group consisting of: treatment with a particular enzyme or class of enzymes; exposure to light, heat or other electromagnetic radiation; displacement by a stronger ligand; amide hydrolysis; treatment with an acid; treatment with a base; treatment with a particular chemical or chemical species; treatment with a particular ion or ionic species; hydrolysis; nucleophilic catalysis; or combinations of two or more of the above. The detectable units may be independently selected from the group consisting of: cyanine, xanthines, squarines, Rhodamines, phycobiliproteins, polymethines, phenoxazines thiazines, croconic acid (see figures 3 and 4). The invention further relates to methods of making detectable compositions and to detection techniques, especially immunoassays. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11370922-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11685835-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016183185-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3037820-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3037821-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11453783-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3294811-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020216439-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2020178705-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11352502-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11434377-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3489684-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3916393-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11390754-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11434374-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11377563-B2 |
| priorityDate | 2001-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 59.