http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2334577-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c01f70afd053f8f4b4221ce2ef40a41c |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57496 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-32 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574 |
| filingDate | 1998-02-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1fbdbd8aae927fd875aa6385c702cad9 |
| publicationDate | 1999-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-2334577-A |
| titleOfInvention | Resistance of p53 mutant cancer cells to cytoxic effects of (chemo)therapeutic agents involving assay of cyclin D1 protein |
| abstract | The measurement of the resistance of p53 cancer cells to the cytotoxic effects of chemotherapeutic agents comprises assay of a sample comprising p53 mutant cells, or an extract therefrom, for the level of cyclin D1 protein. The agent may be a platination agent, especially CDDT (cis-diaminedichloro-platinum). The level of cyclin D1 may be determined either from the mRNA thereof, especially involving a probe therefor, or by contacting the sample with a labelled antibody against cyclin D1 protein. Mutant cells may be identified using an antibody against mutant p53. A kit, for performing the process, is described. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1551990-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1282815-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110196327-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1551990-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110196327-A |
| priorityDate | 1998-02-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 154.