| abstract |
An aminolactone of the formula (I), <IMAGE> is produced by a process, in which a) a compound of the general formula (III), wherein R represents a C1-6 alkyl group, <IMAGE> is subjected to reduction to yield a compound of the general formula (II> <IMAGE> wherein R has the same meaning as defined above, and the compound so obtained, in the presence of an alkanecarboxylic acid having a lower alkyl chain in the alkane moiety, is treated with a complex hydride and then with concentrated aqueous hydrochloric acid to yield the compound of the formula (I), or a2) a compound of the general formula (II), wherein R has the same meaning as defined above, in the presence of an alkanecarboxylic acid having a lower alkyl chain in the alkane moiety, is treated with a complex hydride and then with concentrated aqueous hydrochloric acid to yield the compound of the formula (I). The compound (I) is an intermediate for the known biotic thienamycin and related compounds. |