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filingDate 1975-01-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 1978-02-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber GB-1499582-A
titleOfInvention Substituted tetrahydrobenzothiophenes
abstract The novel compounds correspond to the formula: <IMAGE> in which X, Y, Z, R1, R2, R3 and U have the meanings given in Claim 1. They are prepared by a) reacting one mol equivalent of a compound of the formula I or II, in which the -NR1-CX-NHR1 radical is replaced, or its acid addition salts with 1 to 1.5 mol equivalents of R2NCX or b) reacting one mol equivalent of an acid addition salt of a compound of the formula I or II, in which R2 and R3 denotes hydrogen and the -NR1-CX-NHR2 radical is replaced by -NHR1, with 1 to 1.5 mol equivalents of a compound of the formula MeNCX, in which Me denotes sodium or potassium, and isolating the product. The reaction (a) is carried out in water or an inert organic solvent at 0 to 100 DEG C. The reaction (b) is carried out in aqueous medium at pH = 5 to 7 and 10 to 80 DEG C. The novel compounds of the formulae I and II are administered orally to warm-blooded animals to improve the extent of the feed effect and to increase the growth rate. A supplementary feed for increasing the growth rate of poultry, fur-bearing animals and agricultural productive animals contains 70 to 99% by weight of an edible carrier and, as the remainder, a novel compound of the formula I or II.
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http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1801098-A1
priorityDate 1974-01-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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Total number of triples: 47.