http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1434323-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_47f42150ad988b370e97ab2dee4e863a |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-182 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-15 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D243-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-182 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-495 |
| filingDate | 1974-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1976-05-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-1434323-A |
| titleOfInvention | N-acylated substituted piperazine or homopiperazine derivatives and processes for their preparation |
| abstract | 1434323 N-Acylated substituted piperazine and homopiperazine derivatives ICHTHYOLGES CORDES HERMANNI & CO 28 Jan 1974 [29 Jan 1973] 3784/74 HeadingC2C The invention comprises compounds of Formula (I) in which R is C 4 to C 12 alkyl, n is 1 or 2 and Ar is phenyl, or a 4-chloro-, 2,6-dichloro-, 2-chloro-6- methyl-, 2-chloro-6-butyl-, 2,6-dimethyl-, 3- trifluoromethyl-, 4-methoxy- or 4-n-octyloxyphenyl group, and pharmacuetically or therapeutically acceptable addition salts with acids. They may be prepared by reacting a piperazine or homopiperazine derivative of Formula (III) with an acid derivative, capable of N-acylation, of Formula (IV) in which R 1 is a halogen atom or a C 1 to C 3 alkoxy group, in a polar and/or apolar solvent or in a mixture of these with an aprotic solvent and in the presence of a base. They may also be prepared by reacting an N-acylated piperazine or homopiperazine derivative of Formula (V) with a halogen acetyl derivative (VI) in which R 2 is a halogen atom in a polar and/or apolar solvent or in a mixture of these with an aprotic solvent and in the presence of a base. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6972290-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102656151-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4585774-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7268140-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6977258-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6534509-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011026241-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10208023-B2 |
| priorityDate | 1973-01-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 31.