abstract |
The invention relates to novel products of formula (I): wherein Ra, Rb independently represent H, Hal or alkyl optionally substituted by one or more Hal; Rc is OH or NH2 or alkoxy; R1 represents optionally substituted aryl or heteroaryl; R represents H or forms with R1 a 5- or 6-membered ring fused to an aryl or heteroaryl residue optionally containing one or more O, S, N, NH and Nalk, being optionally substituted; these products being in all isomeric forms and salts, as medicaments in particular as inhibitors of phosphorylation of AKT (PKB). |