abstract |
Compounds of formula (1): in which: R 1 represents: a phenyl group or a naphthyl group, these two groups possibly being able to be substituted; X represents from 1 to 4 identical or different substituents of each other selected from hydrogen, halogen, (C1-C10) alkyl, halo (C1-C10) alkyl, (C1-C10) alkoxy, NRaRb, cyano, nitro ,; R represents in position 3, 5, 7, 8 of the imidazo [1,2-alpha] pyridine of 1 to 4 substituents identical or different from each other; R2 and R3 represent, independently of each other, a hydrogen atom, a (C1-C10) alkyl group optionally substituted; an optionally substituted aryl group; R2 and X together with the carbon atoms carrying them can form a carbon ring of 5 to 7 carbon atoms; R4 represents: a hydrogen atom, an optionally substituted (C1-C10) alkyl group, or an aryl group optionally substituted by one or more substituents.Use in therapy and synthetic method. |