| abstract |
The invention relates to the derivatives of general formula (I) in which: X represents an optionally substituted phenyl group, R1 represents a hydrogen atom, a halogen, an optionally substituted (C1-C6) alkoxy group, a (C1- C6) optionally substituted alkyl, (C3-C7) cycloalkyl (C1-C6) alkyl, (C3-C7) cycloalkyl (C1-C6) alkoxy, hydroxy, amino; R2 represents one of the following groups: a hydrogen atom, an optionally substituted (C1-C6) alkyl group, an optionally substituted (C1-C6) alkoxy group, a (C3-C7) (C1-C6) cycloalkyl group alkyl, a (C 3 -C 7) cycloalkyl (C 1 -C 6) alkoxy group, a (C 2 -C 6) alkenyl group, a (C 2 -C 6) alkynyl group, a -CO-R 5 group a -CO-NR 6 R 7 group - CO-O-R8 a group -NR9-CO-R10 a group -NR11R12 a halogen atom, a cyano group, an optionally substituted phenyl group; R3 represents a hydrogen atom, a (C1-C6) alkyl group or a halogen atom, R4 represents a hydrogen atom or a halogen atom, in the form of a base or of a salt of addition to an acid.Process of preparation and application in therapeutics. |