| abstract |
The subject of the present invention is a process for preparing a stable medicinal solution intended for oral administration, containing agents controlling the release of the active component, characterized in that 1 to 20 parts (by weight) are reacted ) a beta-blocker, in 100 parts of water with 0.001 to 10 parts of a polysaccharide, the temperature of the solution being maintained at 80 degrees C for 20 minutes; the pH of the mixture is then adjusted in the range from 2 to 4.5, using a buffer system, then an antioxidant and a preservative are added, to produce, completing the preparation with water , a suitable solution for oral administration. |